EMIQ

EMIQ is a form of quercetin that is dramatically better absorbed than others (40x better).

This is the form I’ve personally found most effective for mast cell and histamine intolerance symptoms.

Quercetin helps to stabilize mast cells, reducing the release of histamine and other inflammatory mediators.

A few things to know about it:

Quercetin, a dietary flavonol known to be one of the most potent plant-derived antioxidants, has multiple biological actions, with anti-inflammatory, anti-thrombotic and vasodilatory benefits in pre-clinical studies. It also improves zinc absorption into cells.

The limiting factor in quercetin’s clinical efficacy appears to be its poor bioavailability. Enzymatically modified isoquercitrin (EMIQ) is a mixture of quercetin monoglucoside and its alpha-oligoglucosides that has been shown to have significantly greater bioavailability than other available forms. In animals, EMIQ was shown to produce a 40 fold increase in Cmax (peak plasma concentration) and an 18-fold increase in the area under the curve compared to quercetin. In humans, EMIQ supplementation increased plasma concentrations to a significantly greater degree than other forms, including aglycone and isoquercitrin, with randomized placebo-controlled trials documenting improvement in allergic symptoms. EMIQ has also shown significantly enhanced biological activity especially in animal models of allergy and neoplasia.

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